Pharmaceutical Chemistry: Drugs and Their Biological Targets

Joaquín M. Campos Rosa

Published by De Gruyter 2024

Pharmaceutical Chemistry

Drugs and Their Biological Targets

Joaquín M. Campos Rosa

https://doi.org/10.1515/9783111316888

Overview
Contents

About this book

Pharmaceutical chemistry (PC) represents a dynamic field of research that plays a pivotal role in the development of life-saving pharmaceuticals. PC is a precise science: One needs to rely on the accuracy of previous discoveries that have provided massive amount of precious information and databases as a solid foundation to move forward. PC is also an art where the artist uses a subtle mixture of knowledge, experimental learning, creativity, intuition, boldness, and serendipity to paint the right canvas.

Nature often serves as a stimulus for pharmaceutical chemists. Many drugs are derived from natural compounds found in plants, fungi, or microorganisms. Chemists study these natural sources, seeking inspiration to design synthetic molecules that mimic the therapeutic properties of the originals while optimizing their characteristics.

Francis Collins, geneticist and expert in the pharmaceutical industry, explains that the molecular cause of 4,000 diseases is no longer a secret to humanity, but there are only treatments available for 250 of them. Therefore, the world requires more professionals who can produce better medicines and solve more needs. For this reason, it is urgent to discover a new system, new drugs, better industrial processes and faster responses for rare and complex diseases. That is the importance and need for more students in love with PC.

It is the author's wish that volumes 1 and 2 of this series may serve as motivation for students who intend to get started in the exciting world of drug design, synthesis and development. There is no nobler objective than improving health and quality of life of the human race. The unprecedented increase in human life expectancy, which has almost doubled in a hundred years, is mainly due to drugs and to those who discovered them. It is more important to create awareness in the student that he/she is responsible for his own learning and not simply a passive consumer of information. In this way we will be able to train versatile professionals with an attitude of transformative social change.

Drug Design and Action is trated in a separate volume ISBN 978-3-11-131654-3.

Provides a multidisciplinary approach to the field.
Includes case studies and practical examples.

Author / Editor information

Prof. Joaquín Campos obtained his PhD in Organic Chemistry at University of Granada in 1981. Since 1988 he has been working as a professor of medicinal chemistry at the same university. Prof. Campos serves as the editorial board member in Open Journal of Medicinal Chemistry and is the author of 2 textbooks.

Topics

Frontmatter Publicly Available Download PDF	I
Preface to the first edition Publicly Available Download PDF	VII
Preface to the second edition Publicly Available Download PDF	XIII
Contents Publicly Available Download PDF	XV
About the author Publicly Available Download PDF	XXIII
1 Acetylcholine Requires Authentication Unlicensed Licensed Download PDF	1
2 Noradrenaline (norepinephrine) Requires Authentication Unlicensed Licensed Download PDF	37
3 Dopamine Requires Authentication Unlicensed Licensed Download PDF	63
4 Serotonin and reuptake inhibitors of biogenic amines Requires Authentication Unlicensed Licensed Download PDF	83
5 Amino acid neurotransmitters Requires Authentication Unlicensed Licensed Download PDF	97
6 Peptides as neurotransmitters: narcotic analgesics Requires Authentication Unlicensed Licensed Download PDF	115
7 Histamine and antihistamines Requires Authentication Unlicensed Licensed Download PDF	141
8 Enzymatic inhibitors I Requires Authentication Unlicensed Licensed Download PDF	175
9 Enzymatic inhibitors II Requires Authentication Unlicensed Licensed Download PDF	185
10 Design of drugs acting on transport through biological membranes Requires Authentication Unlicensed Licensed Download PDF	200
11 Enzymatic inhibition: inhibitors of the biosynthesis of the cellular wall Requires Authentication Unlicensed Licensed Download PDF	212
12 Enzymatic inhibition: other antibacterial agents Requires Authentication Unlicensed Licensed Download PDF	239
13 Enzymatic inhibition: inhibitors of biosynthesis of nitrogenous bases Requires Authentication Unlicensed Licensed Download PDF	259
Index Requires Authentication Unlicensed Licensed Download PDF	277

(Deutsch)

Language: English
Publisher: De Gruyter
Edition: 2nd, Revised and Extended Edition
Audience: Students, Pharmaceutical Chemists, Organic Chemists, Biochemists, Pharmacists, Drug Developers.
Pages
- Front matter: 24
- Main content: 280
Illustrations
- Illustrations: 6
- Coloured Illustrations: 398
- Tables: 2
Keywords: Drug; Neurotransmitter; Pharmaceutical Chemistry; Drug Design; Active Ingredient

eBook

Published: May 6, 2024
ISBN: 9783111316888

Paperback

Published: May 6, 2024
ISBN: 9783111316550